Convergent In vivo and In Vitro Selection of Ceftazidime Resistance Mutations at Position 167 of CTX-M-3 beta-lactamase in Hypermutable Escherichia coli Strains.

PMID: 182121092008

Key Findings

The study identifies CTX-M-42, a Pro167Thr variant of CTX-M-3, which confers increased ceftazidime resistance. The mutation was selected in vivo and in vitro in hypermutable E. coli strains.

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4gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCTX-M	1	extended-spectrum beta-lactamase	CeftazidimeAZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINCEFEPIMEAMPICILLINCEFOTAXIMECEFTAZIDIME+2 more	Escherichia coli E. coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Browse Papers

Convergent In vivo and In Vitro Selection of Ceftazidime Resistance Mutations at Position 167 of CTX-M-3 beta-lactamase in Hypermutable Escherichia coli Strains.

AMR Genes