Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins.

PMID: 18509701991

Key Findings

Mutant enzymes required 10 times more drug to inhibit reaction

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83A	-	-	Escherichia coli	ciprofloxacin	Reslit	-
gyrA	Q106R	-	-	Escherichia coli	ciprofloxacin	Reslit	-