Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.

PMID: 186257722008France|Israel

Key Findings

The study identifies and characterizes the KPC-2 beta-lactamase, a broad-spectrum class A enzyme responsible for resistance to carbapenems and cephalosporins in Escherichia coli and Enterobacter cloacae strains isolated from the same patient in France.

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6gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaKLUC	1	chromosomal beta-lactamase	CephalosporinAZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINCEFEPIMEAMPICILLINCEFOTAXIMECEFTAZIDIME+2 more	Enterobacter cloacae	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.

AMR Genes