Penicillin resistance in the intestinal spirochaete Brachyspira pilosicoli associated with OXA-136 and OXA-137, two new variants of the class D beta-lactamase OXA-63.

PMID: 187191822008Australia|Papua New Guinea

Key Findings

The study identifies OXA-136 and OXA-137, two new variants of the class D beta-lactamase OXA-63, which are associated with penicillin resistance in Brachyspira pilosicoli. These genes were shown to confer penicillin resistance when expressed in Escherichia coli.

View on PubMed

14gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaOXA	3	class D beta-lactamase	PenicillinBETA-LACTAMAMOXICILLINAMPICILLINUNKNOWN BETA-LACTAM	Brachyspira pilosicoli Escherichia coli Brachyspira pilosicoli WesB	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

Penicillin resistance in the intestinal spirochaete Brachyspira pilosicoli associated with OXA-136 and OXA-137, two new variants of the class D beta-lactamase OXA-63.

AMR Genes