Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness.

PMID: 187616892008

Key Findings

Confers higher in vitro resistance and in vivo fitness compared to other mtrR mutations

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mtrR	A39T	-	-	Neisseria gonorrhoeae	Triton X-100\|erythromycin\|azithromycin\|kanamycin\|progesterone\|CRAMP-38	Reslit	-
mtrR	E202G	-	-	Neisseria gonorrhoeae	Triton X-100\|erythromycin\|azithromycin\|kanamycin\|progesterone\|CRAMP-38	Reslit	-