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Key Findings
Some mutations in the rpoB gene can reveal drug-resistant phenotype only in a specific genetic background of the host.
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| rpoB | Q513L | - | Mycobacterium tuberculosis | rifampin | Reslit | - | |
| rpoB | H526D | - | Mycobacterium tuberculosis | rifampin | Reslit | - | |
| rpoB | D516Y | - | Mycobacterium tuberculosis | rifampin | Reslit | - | |
| rpoB | D516G | - | Mycobacterium tuberculosis | rifampin | Reslit | - | |
| rpoB | D516V | - | Mycobacterium tuberculosis | rifampin | Reslit | - | |
| rpoB | S531L | - | Mycobacterium tuberculosis | rifampin | Reslit | - |
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