New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.

PMID: 196203302009Bulgaria

Key Findings

The study identifies a new variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, in a Klebsiella pneumoniae isolate from Bulgaria, characterized by a Gly238Cys substitution that reduces hydrolytic activity against certain beta-lactam antibiotics.

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5gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCTX-M	1	extended-spectrum beta-lactamase	CefotaximeCeftazidimeCefepimeAZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINCEFEPIMEAMPICILLIN+4 more	Klebsiella pneumoniae Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Browse Papers

New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.

AMR Genes