Use of nfsB, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in Neisseria gonorrhoeae.

PMID: 199306472009

Key Findings

Mutations in nfsB lead to loss of nitroreductase activity, resulting in nitrofurantoin resistance.

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
nfsB	G192A	G575C	-	Neisseria gonorrhoeae	nitrofurantoin	Reslit	-