Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.

PMID: 201941152010

Key Findings

The study characterizes the aminoglycoside resistance methyltransferase Sgm from Micromonospora zionensis, which confers resistance to gentamicin and sisomicin by methylating G1405 in 16S rRNA.

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2gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
sgm	1	aminoglycoside resistance methyltransferase	GentamicinSisomicinGENTAMICIN	Micromonospora zionensis	Reference Gene CatalogReslit	-

Browse Papers

Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.

AMR Genes