An RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus.

PMID: 208377522010

Key Findings

The rpoB mutation was shown to confer heteroresistance to vancomycin and daptomycin in S. aureus.

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	A621E	-	The rpoB(A621E) mutation conferred N315ΔIP with the phenotypes of reduced susceptibility to daptomycin and hetero-VISA., single resistance variant	Staphylococcus aureus	Vancomycin\|DaptomycinDaptomycin	ReslitCard Database	-