Polymorphism in ftsI gene and {beta}-lactam susceptibility in Portuguese Haemophilus influenzae strains: clonal dissemination of beta-lactamase-positive isolates with decreased susceptibility to amoxicillin/clavulanic acid.

PMID: 213932062011

Key Findings

Mutations in the ftsI gene are associated with decreased susceptibility to β-lactam antibiotics

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI	V511A	-	-	Haemophilus influenzae	Ampicillin\|Amoxicillin/clavulanic acid	Reslit	-
ftsI	N526K	-	-	Haemophilus influenzae	Ampicillin\|Amoxicillin/clavulanic acid	Reslit	-
ftsI	V547I	-	-	Haemophilus influenzae	Ampicillin\|Amoxicillin/clavulanic acid	Reslit	-
ftsI	N569S	-	-	Haemophilus influenzae	Ampicillin\|Amoxicillin/clavulanic acid	Reslit	-
ftsI	R517H	-	-	Haemophilus influenzae	Ampicillin\|Cefepime	Reslit	-