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Point mutations in Helicobacter pylori's fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reduction.

PMID: 214649132011

Key Findings

Mutations in the fur gene affect metronidazole resistance in H. pylori.

0gene entries

29mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
fur	R3I	-	-	-	Metronidazole	Reslit	-
fur	R3S	-	-	-	Metronidazole	Reslit	-
fur	R3N	-	-	-	Metronidazole	Reslit	-
fur	T41K	-	-	-	Metronidazole	Reslit	-
fur	T41P	-	-	-	Metronidazole	Reslit	-
fur	K57T	-	-	-	Metronidazole	Reslit	-
fur	H99R	-	-	-	Metronidazole	Reslit	-
fur	R3K	-	-	-	Metronidazole	Reslit	-
fur	T41M	-	-	-	Metronidazole	Reslit	-
fur	T41I	-	-	-	Metronidazole	Reslit	-
fur	C78Y	-	-	-	Metronidazole	Reslit	-
fur	E8K	-	-	-	Metronidazole	Reslit	-
fur	T41Q	-	-	-	Metronidazole	Reslit	-
fur	P114S	-	-	-	Metronidazole	Reslit	-
fur	G40D	-	-	-	Metronidazole	Reslit	-
fur	E95G	-	-	-	Metronidazole	Reslit	-