Browse Papers

Explore scientific publications on antimicrobial resistance

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.

PMID: 21681481990

Key Findings

Mutations in the quinolone resistance-determining region of the gyrA gene cause quinolone resistance.

0gene entries

21mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83L	-	Target modification	Escherichia coli	QuinoloneNalidixic acid,Ciprofloxacin	ReslitResFinder Database	-
gyrA	E67K	-	-	Escherichia coli	Quinolone	Reslit	-
gyrA	A67S	-	DNA gyrase subunit A GyrA, single resistance variant, Target modification	Escherichia coli	QUINOLONEFluoroquinolonesNalidixic acid	Reference Gene CatalogCard DatabaseResFinder Database	-
gyrA	G81C	-	DNA gyrase subunit A GyrA, single resistance variant, Target modification	Escherichia coli	QUINOLONEFluoroquinolonesCiprofloxacin+1 more	Reference Gene CatalogCard DatabaseResFinder Database	-
gyrA	S83W	-	DNA gyrase subunit A GyrA, Target modification	Escherichia coli	QUINOLONENalidixic acid,Ciprofloxacin	Reference Gene CatalogResFinder Database	-
gyrA	A84P	-	DNA gyrase subunit A GyrA, single resistance variant	Escherichia coli	QUINOLONEFluoroquinolones	Reference Gene CatalogCard Database	-
gyrA	Q106H	-	DNA gyrase subunit A GyrA, Target modification	Escherichia coli	QUINOLONENalidixic acid,Ciprofloxacin	Reference Gene CatalogResFinder Database	-
gyrA	G81D	-	Target modification	Escherichia coli	CiprofloxacinNalidixic acid,Ciprofloxacin	ResFinder Database	-
gyrA	S83A	-	Target modification	Escherichia coli	Nalidixic acid,Ciprofloxacin	ResFinder Database	-
gyrA	S83V	-	Target modification	Escherichia coli	Nalidixic acid,Ciprofloxacin	ResFinder Database	-
gyrA	Q106R	-	Target modification	Escherichia coli	Nalidixic acid,Ciprofloxacin	ResFinder Database	-