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The beginning of the rpoB gene in addition to the rifampin resistance determination region might be needed for identifying rifampin/rifabutin cross-resistance in multidrug-resistant Mycobacterium tuberculosis isolates from Southern China.

PMID: 220756012012

0gene entries

15mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	H526L	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	S531L	-	-	Mycobacterium tuberculosis	Rifampin\|Rifabutin	Reslit	-
rpoB	Y314T	-	-	Mycobacterium tuberculosis	Rifampin\|Rifabutin	Reslit	-
rpoB	H526S	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	S531W	-	-	Mycobacterium tuberculosis	Rifampin\|Rifabutin	Reslit	-
rpoB	H323T	-	-	Mycobacterium tuberculosis	Rifampin\|Rifabutin	Reslit	-
rpoB	D516V	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	H526D	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	L533P	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	D516Y	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	H526Y	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	V176F	-	-	Mycobacterium tuberculosis	Rifampin\|Rifabutin	Reslit	-
rpoB	D516F	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	H526R	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	P206T	-	-	Mycobacterium tuberculosis	Rifampin\|Rifabutin	Reslit	-