Structures of the class D Carbapenemases OXA-23 and OXA-146: mechanistic basis of activity against carbapenems, extended-spectrum cephalosporins, and aztreonam.

PMID: 238776772013

Key Findings

The study characterizes the class D carbapenemases OXA-23 and OXA-146, highlighting their mechanisms of hydrolyzing carbapenems, extended-spectrum cephalosporins, and aztreonam.

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6gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaOXA	2	class D carbapenemase	CarbapenemCephalosporinsAztreonamCARBAPENEMUNKNOWN BETA-LACTAM	Acinetobacter baumannii	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

Structures of the class D Carbapenemases OXA-23 and OXA-146: mechanistic basis of activity against carbapenems, extended-spectrum cephalosporins, and aztreonam.

AMR Genes