Identification of the novel lincosamide resistance gene lnu(E) truncated by ISEnfa5-cfr-ISEnfa5 insertion in Streptococcus suis: de novo synthesis and confirmation of functional activity in Staphylococcus aureus.

PMID: 243667332014

Key Findings

The study identifies a novel lincosamide resistance gene, lnu(E), which was truncated by an insertion of an IS Enfa5-cfr-IS Enfa5 segment in Streptococcus suis. The gene was synthetically reconstructed and confirmed to confer resistance to lincomycin in Staphylococcus aureus.

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2gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
lnu(E)	2	lincosamide nucleotidyltransferase	LincomycinLINCOMYCIN	Streptococcus suis Staphylococcus aureus synthetic construct	ResFinder DatabaseReslit	-

Browse Papers

Identification of the novel lincosamide resistance gene lnu(E) truncated by ISEnfa5-cfr-ISEnfa5 insertion in Streptococcus suis: de novo synthesis and confirmation of functional activity in Staphylococcus aureus.

AMR Genes