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Key Findings
Multiple mutations in the parC gene contribute to ciprofloxacin resistance.
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| A128S | - | - | Vibrio cholerae | Ciprofloxacin | Reslit | - | |
| S85I | - | The mutation of S85I affects the binding conformation of ciprofloxacin., DNA topoisomerase IV subunit A ParC | Vibrio cholerae | CiprofloxacinQUINOLONE | ReslitReference Gene Catalog | - | |
| K129R | - | - | Vibrio cholerae | Ciprofloxacin | Reslit | - | |
| S60N | - | The mutation of S85I affects the binding conformation of ciprofloxacin. | Vibrio cholerae | Ciprofloxacin | Reslit | - | |
| S83I | - | - | Vibrio cholerae | Ciprofloxacin | Reslit | - | |
| Y65F | - | - | Vibrio cholerae | Ciprofloxacin | Reslit | - |
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