Heteroresistance to Colistin in Klebsiella pneumoniae Associated with Alterations in the PhoPQ Regulatory System.

PMID: 257335032015

Key Findings

The wild-type PhoP protein is part of the PhoPQ regulatory system that activates pmrHFIJKLM expression responsible for l-aminoarabinose synthesis and polymyxin resistance.

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0gene entries

3mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
phoP	D191Y	-	two-component system response regulator PhoP, single resistance variant	Klebsiella pneumoniae	ColistinCOLISTIN	ReslitReference Gene CatalogCard Database	-

Browse Papers

Heteroresistance to Colistin in Klebsiella pneumoniae Associated with Alterations in the PhoPQ Regulatory System.

AMR Mutations