Emergence of a Potent Multidrug Efflux Pump Variant That Enhances Campylobacter Resistance to Multiple Antibiotics.

PMID: 276513642016

Key Findings

The C257T mutation in gyrA enhances fluoroquinolone resistance when combined with RE-cmeABC.

1gene entry

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
cmeB	1	multidrug efflux RND transporter permease subunit CmeB, ciprofloxacin and florfenicol resistance type	QUINOLONEFLORFENICOL	Campylobacter jejuni	Reference Gene Catalog	-

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	-	C257T	-	Campylobacter coli, Campylobacter jejuni	Fluoroquinolones	Reslit	-