The polymyxin B-induced transcriptomic response of a clinical, multidrug-resistant Klebsiella pneumoniae involves multiple regulatory elements and intracellular targets.

PMID: 278012932016South Brazil

Key Findings

The study identified a truncated mgrB gene as a potential mechanism for polymyxin B resistance in a multidrug-resistant Klebsiella pneumoniae strain.

3gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
acrA	1	efflux pump	Fluoroquinolone	Klebsiella pneumoniae	Reslit	-
acrB	1	efflux pump	Fluoroquinolone	Klebsiella pneumoniae	Reslit	-
arnA	1	lipid A modifying enzyme	Polymyxin b	Klebsiella pneumoniae