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Structure-Function Analysis of the Transmembrane Protein AmpG from Pseudomonas aeruginosa.

PMID: 279599422016

Key Findings

Mutations in ampG lead to loss of function and decreased resistance to ampicillin

0gene entries

44mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampG	Q131P	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	Q131R	-	loss of function	Escherichia coli, Vibrio cholerae, Pseudomonas aeruginosa, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	Q131H	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	A197S	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	A197D	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	G29V	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	A129T	-	loss of function	Escherichia coli, Vibrio cholerae, Acinetobacter baumannii, Pseudomonas aeruginosa	Ampicillin	Reslit	-
ampG	A129V	-	loss of function	Vibrio cholerae, Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli	Ampicillin	Reslit	-
ampG	A129D	-	loss of function	Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae	Ampicillin	Reslit	-
ampG	G29A	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-
ampG	Q131E	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	Ampicillin	Reslit	-