Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.

PMID: 280990012017

Key Findings

Mutations in PBP2a affect allosteric communication and resistance to β-lactam antibiotics

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2a	E150K	-	altered allosteric communication	Staphylococcus aureus	Ceftaroline	Reslit	-