Primary structure of an aminoglycoside 6'-N-acetyltransferase AAC(6')-4, fused in vivo with the signal peptide of the Tn3-encoded beta-lactamase.

PMID: 28244441987

Key Findings

The aacA4 gene encoding an aminoglycoside 6'-N-acetyltransferase, AAC(6')-4, was cloned and its nucleotide sequence was determined. The gene was found to be part of a resistance gene cluster and was under the control of the regulatory sequences of the beta-lactamase encoded by Tn3.

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1gene entry

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
aacA4	1	aminoglycoside 6'-N-acetyltransferase	Amikacin	Escherichia coli	Reslit	-

Browse Papers

Primary structure of an aminoglycoside 6'-N-acetyltransferase AAC(6')-4, fused in vivo with the signal peptide of the Tn3-encoded beta-lactamase.

AMR Genes