Genetic and Functional Characterization of blaCTX-M-199, a Novel Tazobactam and Sulbactam Resistance-Encoding Gene Located in a Conjugative mcr-1-Bearing IncI2 Plasmid.

PMID: 284839542017China

Key Findings

The study identifies and characterizes a novel beta-lactamase, blaCTX-M-199, which confers resistance to tazobactam and sulbactam. This gene is located on a conjugative mcr-1-bearing IncI2 plasmid and exhibits resistance to beta-lactamase inhibitors.

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5gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCTX-M	1	beta-lactamase	AZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINCEFEPIMEAMPICILLINCEFOTAXIMECEFTAZIDIMECEFTRIAXONE+1 more	Escherichia coli E. coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

Genetic and Functional Characterization of blaCTX-M-199, a Novel Tazobactam and Sulbactam Resistance-Encoding Gene Located in a Conjugative mcr-1-Bearing IncI2 Plasmid.

AMR Genes