Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants Selected by Tobramycin.

PMID: 285841562017

Key Findings

AxyZ; CARD accession: CARD:3004145

0gene entries

3mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
axyZ	V29G	T86G	single resistance variant, overproduction of the AxyXY-OprZ efflux system	Achromobacter insuavis, Achromobacter xylosoxidans	Tobramycin\|Amikacin\|Gentamicin\|Netilmicin\|Ceftazidime\|Cefepime\|Imipenem\|Meropenem\|Doripenem\|Ofloxacin\|Levofloxacin\|Ciprofloxacin\|Tetracycline\|Doxycycline\|Tigecycline\|Erythromycin	Card DatabaseReslit	-