The PK-PD Relationship and Resistance Development of Danofloxacin against Mycoplasma gallisepticum in An In Vivo Infection Model.

PMID: 286117392017

Key Findings

Mutations in gyrA and parC were identified in resistant mutant strains.

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83R	-	-	Mycoplasma gallisepticum	Danofloxacin\|Enrofloxacin\|Ofloxacin\|Levofloxacin\|Gatifloxacin\|Norfloxacin	Reslit	-
gyrA	E87G	-	-	Mycoplasma gallisepticum	Danofloxacin\|Enrofloxacin\|Ofloxacin\|Levofloxacin\|Gatifloxacin\|Norfloxacin	Reslit	-
parC	E84K	-	-	-	Danofloxacin\|Enrofloxacin\|Ofloxacin\|Levofloxacin\|Gatifloxacin\|Norfloxacin	Reslit	-