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High-Level Resistance to Colistin Mediated by Various Mutations in the crrB Gene among Carbapenemase-Producing Klebsiella pneumoniae.

PMID: 288743772017

Key Findings

mutations in crrB gene associated with colistin resistance

0gene entries

8mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
crrB	G183V	-	HAMP domain-containing histidine kinase CrrB	Klebsiella pneumoniae	ColistinCOLISTIN	ReslitReference Gene Catalog	-
crrB	P151L	-	HAMP domain-containing histidine kinase CrrB	Klebsiella pneumoniae	ColistinCOLISTIN	ReslitReference Gene Catalog	-
crrB	F84S	-	HAMP domain-containing histidine kinase CrrB	Klebsiella pneumoniae	ColistinCOLISTIN	ReslitReference Gene Catalog	-
crrB	N141Y	-	HAMP domain-containing histidine kinase CrrB	Klebsiella pneumoniae	ColistinCOLISTIN	ReslitReference Gene Catalog	-