Contribution of Novel Amino Acid Alterations in PmrA or PmrB to Colistin Resistance in mcr-Negative Escherichia coli Clinical Isolates, Including Major Multidrug-Resistant Lineages O25b:H4-ST131-H30Rx and Non-x

PMID: 299149522018

0gene entries

4mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB	G206D	-	two-component system sensor histidine kinase PmrB	Escherichia coli	ColistinCOLISTIN	ReslitReference Gene Catalog	-
pmrA	L105P	-	activates eptA and arnT	Escherichia coli	Colistin	Reslit	-
basR	L105P	-	two-component system response regulator BasR	Escherichia coli	COLISTIN	Reference Gene Catalog	-