Key Findings

The paper discusses the mechanisms of carbapenem and polymyxin resistance in Enterobacteriaceae, highlighting the role of beta-lactamases such as blaKPC, blaNDM, and blaOXA-48, as well as mcr-1, mcr-2, mcr-3, mcr-5, and mcr-9 genes. It also identifies mutations in envZ, ompR, pmrAB, and phoPQ that contribute to resistance.