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Explore scientific publications on antimicrobial resistance
Explore scientific publications on antimicrobial resistance
Key Findings
mutations in pbp4 promoter and gene mediate β-lactam resistance
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| E218K | - | increased survival in the presence of the β-lactams nafcillin and cefoxitin, D-alanyl-D-alanine carboxypeptidase PBP4 | Staphylococcus aureus | Nafcillin|CefoxitinCEPHALOSPORIN | ReslitReference Gene Catalog | - | |
| R200L | - | increased survival in the presence of the β-lactams nafcillin and cefoxitin, D-alanyl-D-alanine carboxypeptidase PBP4 | Staphylococcus aureus | Nafcillin|CefoxitinCEPHALOSPORIN | ReslitReference Gene Catalog | - | |
| - | D-alanyl-D-alanine carboxypeptidase PBP4 promoter region | Staphylococcus aureus | CEPHALOSPORIN | Reference Gene Catalog | - |
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