Escherichia coli strains possessing a four amino acid YRIN insertion in PBP3 identified as part of the SIDERO-WT-2014 surveillance study.

PMID: 342230332020

Key Findings

The YRIN insertion in PBP3 reduces susceptibility to several β-lactam antibiotics.

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI	I532L	-	-	Escherichia coli	Ceftazidime\|Ceftolozane/tazobactam\|Cefepime\|Aztreonam	Reslit	-
ftsI	E349K	-	-	Escherichia coli	Ceftazidime\|Ceftolozane/tazobactam\|Cefepime\|Aztreonam	Reslit	-