Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study.

PMID: 347660682021

Key Findings

The rpoB mutation Ser450Leu was identified as a rifampicin resistance-conferring mutation in the study.

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	S450L	AGC->CTC	-	-	Rifampicin	Reslit	-