Key Findings

The study identified several AMR genes and mutations in ertapenem-non-susceptible Enterobacterales, including carbapenemases (NDM-5, OXA-181), beta-lactamases (TEM-1B, CTX-M-71), and mutations in PBP3 and porin genes (ompC, ompF) that contribute to resistance against cefepime/taniborbactam and other beta-lactam antibiotics.