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Repeated Exposure of Escherichia coli to High Ciprofloxacin Concentrations Selects gyrB Mutants That Show Fluoroquinolone-Specific Hyperpersistence.

PMID: 357071702022

Key Findings

The mutation is outside the canonical GyrB QRDR.

0gene entries

1mutation entry

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB	L422P	-	-	Escherichia coli	Ciprofloxacin	Reslit	-