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Key Findings
The study identified novel variants of aminoglycoside and beta-lactam resistance genes, including aph(3')-IIc, aph(6), ant(6), IND-17, and CHM, which confer resistance to kanamycin, streptomycin, and various beta-lactam antibiotics.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| ant(6)-Ia | 1 | aminoglycoside 6-adenylyltransferase | Streptomycin |
| Reslit | - |
| aph(3')-IIc | 1 | aminoglycoside O-phosphotransferase | Kanamycin |
| Reslit | - |
| aph(6) | 1 | aminoglycoside O-phosphotransferase | Streptomycin |
|
Reslit |
| - |
| blaCHM | 1 | subclass B1 metallo-beta-lactamase CHM-1 | CARBAPENEM |
| Card DatabaseReference Gene Catalog | - |
| blaIND | 1 | subclass B1 metallo-beta-lactamase IND-17, IND beta-lactamase | CARBAPENEMImipenem |
| Card DatabaseReference Gene CatalogReslit | - |
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