Amino acid substitutions in PBP3 in Haemophilus influenzae strains, their phenotypic detection and impact on resistance to β-lactams.

PMID: 398953692025

0gene entries

20mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI	N526K	AAT->AAA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	T532S	ACC->TCC	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	M377I	ATG->ATA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	I519L	ATT->CTT	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	I449V	ATT->GTT	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	P408S	CCC->AGC	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	R517H	CGT->CAT	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	R501C	CGT->TGT	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	L389F	CTT->TTT	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	D350N	GAT->AAC	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	A502T	GCA->ACA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	A502V	GCA->GTA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	A437S	GCA->TCA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	A530S	GCA->TCA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	G490E	GGT->GAA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	V418A	GTA->GCC	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	V461I	GTT->ATA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	S357N	TCA->AAC	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	S385T	TCA->ACA	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-
ftsI	S406G	TCA->GGG	-	Haemophilus influenzae	Ampicillin\|Penicillin	Reslit	-