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Key Findings
Mutations in the rpoB gene were associated with rifampicin resistance in clinical S. epidermidis isolates.
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| Q468L | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus epidermidis | RifampicinRIFAMPIN | ReslitReference Gene Catalog | - | |
| Q468K | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| D471Y | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| H481C | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus epidermidis | RifampicinRIFAMPIN | ReslitReference Gene Catalog | - | |
| H481N | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| H481Y | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| S486F | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| S486Y | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| L466S | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus epidermidis | RifampicinRIFAMPIN | ReslitReference Gene Catalog | - | |
| D471E | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| I527M | - | - | Staphylococcus epidermidis | Rifampicin | Reslit | - | |
| S529L | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus epidermidis | RifampicinRIFAMPIN | ReslitReference Gene Catalog | - |
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