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The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China.

PMID: 400254562025

Key Findings

Mutations in embB are strongly associated with ethambutol resistance.

0gene entries

16mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
embB	M306V	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	D328Y	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	T581A	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	G406A	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	D354A	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	D1024N	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	G406D	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	Q497H	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	Q497R	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	Q497P	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	M306I	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	G406S	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	L402V	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	M306L	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	V50A	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	F330I	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-