Lytic Transglycosylase Deficiency Increases Susceptibility to β-lactam Antibiotics But Reduces Susceptibility to Vancomycin in Escherichia coli.

PMID: 404181772025

Key Findings

The E505A mutation in slt does not restore the wild-type phenotype

1gene entry

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
slt	1	lytic transglycosylase	Vancomycin	Escherichia coli	Reslit	-

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
slt	E505A	G1514A	-	Escherichia coli	Vancomycin	Reslit	-