Driving factors for beta-lactam resistance gene amplification during de novo resistance evolution in E. coli.

PMID: 406988182025

Key Findings

The study identifies ampC and tet(B) as key genes involved in beta-lactam and tetracycline resistance, respectively, through genomic amplification and mutations in E. coli.

View on PubMed

1gene entry

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
tet(B)	1	tetracycline resistance protein	Tetracycline	Escherichia coli	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
acrB	V348I	-	-	Escherichia coli	Tetracycline	Reslit	-
mrcB	-	T135G	-	Escherichia coli	-	Reslit	-

Browse Papers

Driving factors for beta-lactam resistance gene amplification during de novo resistance evolution in E. coli.

AMR Genes

AMR Mutations