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Idiosyncratic evolvability among single-point ribosomal mutants towards multi-aminoglycoside resistance.

PMID: 408539852025

Key Findings

mutations in rpsL affect ribosomal structure and confer resistance to aminoglycosides

0gene entries

9mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpsL	K88R	A263C	-	-	Streptomycin\|Amikacin\|Gentamicin\|Kanamycin\|TobramycinStreptomycin	Reslit	-
rpsL	K43N	A128T	-	-	Streptomycin\|Amikacin\|Gentamicin\|Kanamycin\|TobramycinStreptomycin	Reslit	-
rpsL	P91Q	-	-	-	Streptomycin\|Amikacin\|Gentamicin\|Kanamycin\|Tobramycin	Reslit	-
rpsL	K43T	-	-	-	Streptomycin\|Amikacin\|Gentamicin\|Kanamycin\|Tobramycin	Reslit	-
rpsL	K88E	A263G	-	-	Streptomycin\|Amikacin\|Gentamicin\|Kanamycin\|TobramycinStreptomycin	Reslit	-
rpsL	K91Q	A272C	-	-	Streptomycin	Reslit	-