Allele-specific effects of mutations in the rifampin resistance-determining region (RRDR) of RpoB on physiology and antibiotic resistance in Enterococcus faecium.

PMID: 413425322025

Key Findings

Mutations in the RpoB gene's rifampin resistance-determining region (RRDR) were found to confer rifampin resistance in Enterococcus faecium.

0gene entries

4mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	Q473K	-	-	Enterococcus faecium	Rifampin	Reslit	-
rpoB	G482D	-	-	Enterococcus faecium	Rifampin	Reslit	-
rpoB	H486Y	-	-	Enterococcus faecium	Rifampin	Reslit	-
rpoB	S491L	-	-	Enterococcus faecium	Rifampin	Reslit	-