Evolutionary trajectories determine feasibility of collateral sensitivity-based antibiotic treatment strategies in critical bacterial pathogens.

PMID: 413532912025

Key Findings

Mutation in sspA leads to collateral sensitivity to gentamicin.

0gene entries

4mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
sspA	E102K	-	-	Escherichia coli	Gentamicin	Reslit	-
tusC	G102R	-	-	Escherichia coli	Gentamicin	Reslit	-
guaA	-	TTG->TGT	inactivation	Escherichia coli	Gentamicin	Reslit	-
metG	-	TTG->TGT	-	Escherichia coli	Gentamicin	Reslit	-