Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.
PMID: 81276691994
0gene entries
9mutation entries
AMR Mutations
| Nucleotide Change | Gene | Protein Change | Effect | Type | Resistance To | Database | Status |
|---|---|---|---|---|---|---|---|
| G1064A | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064A | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064A | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064C | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064C | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064C | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064T | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064T | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |
| G1064T | rrs | - | Target modification | - | Spectinomycin | ResFinder | Not Validated |