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Contribution of mutations in gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro.

PMID: 89134541996

0gene entries

9mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S84F	-	-	Streptococcus pneumoniae	Fluoroquinolones	Reslit	-
parC	S80F	-	-	Streptococcus pneumoniae	Fluoroquinolones	Reslit	-
parC	D84H	-	-	Streptococcus pneumoniae	Fluoroquinolones	Reslit	-
parC	S79F	-	DNA topoisomerase IV subunit A ParC	Streptococcus pneumoniae	QUINOLONE	Reference Gene Catalog	-
parC	S79Y	-	DNA topoisomerase IV subunit A ParC	Streptococcus pneumoniae	QUINOLONE	Reference Gene Catalog	-
parC	D83H	-	DNA topoisomerase IV subunit A ParC	Streptococcus pneumoniae	QUINOLONE	Reference Gene Catalog	-
parC	S82F	-	single resistance variant	Streptococcus pneumoniae	Fluoroquinolones	Card Database	-
parC	D86H	-	single resistance variant	Streptococcus pneumoniae	Fluoroquinolones	Card Database	-
parC	S82Y	-	single resistance variant	Streptococcus pneumoniae	Fluoroquinolones	Card Database	-