Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Isoniazid-resistance conferring mutations in Mycobacterium tuberculosis KatG: catalase, peroxidase, and INH-NADH adduct formation activities.
Research Article
Mutations in KatG are associated with isoniazid resistance through reduced INH-NADH adduct formation.
Antimicrobial Resistance in Mycobacterium tuberculosis Clinical Isolates from HIV-Positive and HIV-Negative Patients in Russia
Research Article
Screening and characterization of mutations in isoniazid-resistant Mycobacterium tuberculosis isolates obtained in Brazil.
Research Article
Multiple mutations in katG codon 315 were identified, including S315T, S315N, and S315R.
Reinfection and mixed infection cause changing Mycobacterium tuberculosis drug-resistance patterns.
Research Article
Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs With Activity Against Mycobacterium tuberculosis.
Research Article
Mutations in katG were associated with resistance to pyridine carboxamide prodrugs and isoniazid.
Prevalence and Molecular Characteristics Based on Whole Genome Sequencing of Mycobacterium tuberculosis Resistant to Four Anti-Tuberculosis Drugs from Southern Xinjiang, China.
Research Article
Mutations in the katG gene are associated with isoniazid resistance.
Off-label evaluation of the BD MAX MDR-TB assay for rapid diagnosis of rifampicin and isoniazid resistance of Mycobacterium tuberculosis clinical isolates in a high-volume reference laboratory.
Research Article
Mutations in katG confer resistance to isoniazid
Integration of published information into a resistance-associated mutation database for Mycobacterium tuberculosis.
Review
Molecular characterisation of multidrug-resistant Mycobacterium tuberculosis isolates from a high-burden tuberculosis state in Brazil.
Research Article
Mutations in codon 315 were found in 106 isolates (80.9%).
Large-scale statistical analysis of Mycobacterium tuberculosis genome sequences identifies compensatory mutations associated with multi-drug resistance.
Research Article
These mutations are associated with isoniazid resistance.
Rapid Identification of Lineage and Drug Resistance in Clinical Samples of Mycobacterium tuberculosis.
Research Article
The mutation katG (Ser315Arg) was not described as conferring resistance, but the strain was isoniazid-resistant.
Prevalence of Mycobacterium tuberculosis mutations associated with isoniazid and rifampicin resistance: A systematic review and meta-analysis.
Research Article
MDR TB transmission, Singapore.
Research Article
Mutations of rpoB, katG, inhA and ahp genes in rifampicin and isoniazid-resistant Mycobacterium tuberculosis in Kyrgyz Republic.
Research Article
Validation of the FluoroType MTBDR Assay for Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Complex Isolates.
Research Article
Identification of katG mutations associated with high-level isoniazid resistance in Mycobacterium tuberculosis.
Research Article
Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid; CARD accession: CARD:3003392
Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.
Research Article
Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid; CARD accession: CARD:3003392
Mycobacterium tuberculosis katG mutations conferring resistance to isoniazid; CARD accession: CARD:3003392
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