Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis.
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Dominant incidence of multidrug and extensively drug-resistant specific Mycobacterium tuberculosis clones in Osaka Prefecture, Japan.
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Frequency of multi-drug resistance and mutations in Mycobacterium tuberculosis isolates from Punjab state of India.
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Mutation in inhA gene for INH resistance
Drug Resistance Conferring Mutation and Genetic Diversity of Mycobacterium tuberculosis Isolates in Tuberculosis Lymphadenitis Patients; Ethiopia.
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One isolate had inhA MUT1 band developed without missing the WT probe
Multidrug-resistant tuberculosis: rapid detection of resistance to rifampin and high or low levels of isoniazid in clinical specimens and isolates.
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Use of the GenoType(R) MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda.
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Importance of the genetic diversity within the Mycobacterium tuberculosis complex for the development of novel antibiotics and diagnostic tests of drug resistance.
Review
Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon? a cross-sectional study.
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Isoniazid resistance profile and associated levofloxacin and pyrazinamide resistance in rifampicin resistant and sensitive isolates/from pulmonary and extrapulmonary tuberculosis patients in Pakistan: A laboratory based surveillance study 2015-19.
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associated with isoniazid resistance
Prevalence and factors associated with multidrug-resistant tuberculosis in South India.
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Whole genome analysis of extensively drug resistant Mycobacterium tuberculosis strains in Peru.
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Associations between Mycobacterium tuberculosis strains and phenotypes.
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Mutations in inhA gene associated with isoniazid resistance
Drug resistance mutations and heteroresistance detected using the GenoType MTBDRplus assay and their implication for treatment outcomes in patients from Mumbai, India.
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Diagnostic Performance of the GenoType MTBDRplus and MTBDRsl Assays to Identify Tuberculosis Drug Resistance in Eastern China.
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Utility of Line Probe Assay for the Early Detection of Multidrug-Resistant Pulmonary Tuberculosis.
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Phenotypic and genotypic analysis of anti-tuberculosis drug resistance in Mycobacterium tuberculosis isolates in Myanmar.
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Primary Multidrug Resistant Tuberculosis and Utility of Line Probe Assay for Its Detection in Smear-Positive Sputum Samples in a Tertiary Care Hospital in South India.
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Evaluation of GenoType MTBDRplus for the detection of drug-resistant Mycobacterium tuberculosis on isolates from Karachi, Pakistan.
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mutation in the inhA promoter region
Isoniazid and Rifampin-Resistance Mutations Associated With Resistance to Second-Line Drugs and With Sputum Culture Conversion.
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The positivity rates and drug resistance patterns of Mycobacterium tuberculosis using nucleotide MALDI-TOF MS assay among suspected tuberculosis patients in Shandong, China: a multi-center prospective study.
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Genotypic and phenotypic drug resistance patterns of Mycobacterium tuberculosis isolated from presumptive pulmonary tuberculosis patients in Ethiopia: A multicenter study.
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Cross-Border Movement of Highly Drug-Resistant Mycobacterium tuberculosis from Papua New Guinea to Australia through Torres Strait Protected Zone, 2010-2015.
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mutation in the promoter region leads to overexpression of the gene, resulting in isoniazid resistance
Genotypic Distribution and the Epidemiology of Multidrug Resistant Tuberculosis in Upper Northern Thailand.
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Mutations in the inhA promoter are associated with isoniazid resistance
Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance.
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InhA promoter region C-15T mutation
First evaluation of an improved assay for molecular genetic detection of tuberculosis as well as rifampin and isoniazid resistances.
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Epidemiology of isoniazid resistance mutations and their effect on tuberculosis treatment outcomes.
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Resistance of Mycobacterium tuberculosis to antibiotics in Lao PDR: first multicentric study conducted in 3 hospitals.
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The C15T mutation in the inhA promoter is associated with isoniazid resistance.
Genotype diversity of Mycobacterium isolates from children in Jimma, Ethiopia.
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The mutation at the inhA locus was associated with low-level resistance to isoniazid and ethionamide.
Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India.
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Correlation between the BACTEC MGIT 960 culture system with Genotype MTBDRplus and TB-SPRINT in multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil.
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Drug Resistance of Mycobacterium tuberculosis Complex in a Rural Setting, Angola.
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Mutations of rpoB, katG, inhA and ahp genes in rifampicin and isoniazid-resistant Mycobacterium tuberculosis in Kyrgyz Republic.
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Genetic Mutations Associated with Isoniazid Resistance in Mycobacterium tuberculosis in Mongolia.
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Molecular detection of multidrug resistance pattern and associated gene mutations in M. tuberculosis isolates from newly diagnosed pulmonary tuberculosis patients in Addis Ababa, Ethiopia.
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