ResLit - Antimicrobial Resistance Gene & Mutation Database

D-serine, L- and D-alanine, and glycine transporter

Protein ChangeG122S

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: cycloserine
Organisms: Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium smegmatis
Papers: 1

Paper Information1

A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains.

Research Article

The G122S mutation in BCG CycA is predicted to lie in an extracellular loop between the third and fourth trans-membrane helices.

Protein Change: G122S
Organisms: Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium smegmatis
Confers Resistance To: cycloserine
Validation Method: sequencing and susceptibility testing
Source Database: Reslit

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