Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.
The Impact of Selected Bacterial Sexually Transmitted Diseases on Pregnancy and Female Fertility.
Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance, a Novel Antimicrobial Resistance Multilocus Typing Scheme for Tracking Global Dissemination of N. gonorrhoeae Strains.
mutations in mtrR lead to overexpression of the MtrCDE efflux pump, contributing to resistance against multiple antimicrobials
Mutation pattern in the genome of Neisseria gonorrhoeae and its association with multidrug-resistant isolates from Delhi, India.
Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae.
Mutations in mtrR contribute to increased resistance when combined with mtrD mutations.
Susceptibility Trends of Zoliflodacin against Multidrug-Resistant Neisseria gonorrhoeae Clinical Isolates in Nanjing, China, 2014 to 2018.
Genomic Epidemiology of Azithromycin-Nonsusceptible Neisseria gonorrhoeae, Argentina, 2005-2019.
Molecular Epidemiology, Antimicrobial Surveillance, and PK/PD Analysis to Guide the Treatment of Neisseria gonorrhoeae Infections.
Mutations in the mtrR gene contribute to azithromycin resistance.
The antimicrobial resistance landscape of Neisseria gonorrhoeae in New Zealand from November 2018 to March 2019 and the role of sexual orientation in transmission.
WGS to predict antibiotic MICs for Neisseria gonorrhoeae.
Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014-2015): genetic characteristics of antimicrobial resistance.
Mutations in mtrR gene are associated with resistance to azithromycin.
Plasmid mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates from Kenya.
Mutations in mtrR are associated with overexpression of the MtrCDE efflux pump, contributing to resistance to penicillin and tetracycline.
Shanghai Neisseria gonorrhoeae Isolates Exhibit Resistance to Extended-Spectrum Cephalosporins and Clonal Distribution.
MtrR mutations G45D and T86A are associated with ESC resistance.
Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae.
Mutations in mtrR are associated with increased resistance to beta-lactams, macrolides, and tetracyclines.
Genetic AMR mechanisms: genotypic and phenotypic benchmarks
Mutations in mtrR and its promoter contribute to increased resistance to tetracycline and azithromycin.
First National Genomic Epidemiological Study of Neisseria gonorrhoeae Strains Spreading Across Sweden in 2016.
Relation between genetic markers of drug resistance and susceptibility profile of clinical Neisseria gonorrhoeae strains.
Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from symptomatic men attending the Nanjing sexually transmitted diseases clinic (2011-2012): genetic characteristics of isolates with reduced sensitivity to ceftriaxone.
Emergence and Spread of Neisseria gonorrhoeae Strains with High-Level Resistance to Azithromycin in Taiwan from 2001 to 2018.
Equations To Predict Antimicrobial MICs in Neisseria gonorrhoeae Using Molecular Antimicrobial Resistance Determinants.
Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution.
Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.
The isolate had the G45D mutation in mtrR and a promoter deletion, leading to over-expression of the MtrCDE efflux pump.
Antimicrobial resistance prediction and phylogenetic analysis of Neisseria gonorrhoeae isolates using the Oxford Nanopore MinION sequencer.
Mutation in mtrR leads to overexpression of the MtrCDE efflux pump, contributing to azithromycin resistance.
Whole genome analysis and antimicrobial resistance of Neisseria gonorrhoeae isolates from Ghana.
Mutations in mtrR were linked to resistance to beta-lactams and macrolides.
Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011.
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.
Results in overexpression of the MtrCDE efflux pump, contributing to resistance.
Phylogeny and antimicrobial resistance in Neisseria gonorrhoeae isolates from Rio de Janeiro, Brazil.
Genomic epidemiology and antimicrobial resistance of Neisseria gonorrhoeae in New Zealand.
Azithromycin resistant gonococci: a literature review.
mutations in mtrR are associated with azithromycin resistance
Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae.
mutations in mtrR contribute to resistance through overexpression of MtrCDE efflux pump
Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness.
mtrR
Neisseria gonorrhoeae mtrR with mutation conferring resistance; CARD accession: CARD:3004851
Missense mutations that alter the DNA-binding domain of the MtrR protein occur frequently in rectal isolates of Neisseria gonorrhoeae that are resistant to faecal lipids.
mtrR; CARD accession: CARD:3000817
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