ResLit - Antimicrobial Resistance Gene & Mutation Database

GenegyrA

Nucleotide ChangeC258T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduces the affinity of fluoroquinolone antibiotics to bind to the enzyme
Resistance To: ciprofloxacin, fluoroquinolones
Organisms: Campylobacter jejuni, Campylobacter coli
Papers: 2

Paper Information2

Antimicrobial resistance of Campylobacter isolates from small scale and backyard chicken in Kenya.

Research Article

PMID 27570543 · 2016

Mutation Information

gyrA: c.C258T

Nucleotide Change: C258T
Organisms: Campylobacter jejuni, Campylobacter coli
Confers Resistance To: ciprofloxacin
Validation Method: MAMA-PCR and PCR-RFLP
Source Database: Reslit

Antimicrobial resistance and interspecies gene transfer in Campylobacter coli and Campylobacter jejuni isolated from food animals, poultry processing, and retail meat in North Carolina, 2018-2019.

Research Article

PMID 33571292 · 2021

Mutation Information

gyrA: c.C258T

Nucleotide Change: C258T
Organisms: Campylobacter coli, Campylobacter jejuni
Confers Resistance To: fluoroquinolones
Effect on Function: reduces the affinity of fluoroquinolone antibiotics to bind to the enzyme
Validation Method: genomic analysis
Source Database: Reslit

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